PURE VITALITY - ARGININE (LRG-9)

WHEN TAKING YOUR Arginine (LRG-9)

Please take your ARGININE(LRG-9) on an empty stomach. The stomach empties approximately 45 minutes after eating. Dr. Louis J. Ignarro states in his book, "No More Heart Disease", ARGININE (LRG-9) is particularly effective in aiding the management of high blood pressure, diabetes, heart disease and other potential issues.

Pure Vitality LRG-9 COMPLETE

A HIDDEN SECRET TO THE FOUNTAIN OF YOUTH

Feeling Run Down?

Lost Your Energy?

Looking Old?

Want to find your youth?

Here is the good news...there is actually a way to do that.

Considered a breakthrough discovery that was validated by a Nobel Prize in Medicine in 1998, doctors found that the amino acids L-arginine and L-citrulline create Nitric Oxide when in the body. When the body produces Nitric Oxide (NO), it causes blood vessels to dilate, which increases blood flow to muscles and vital organs, including the heart. This allows for the delivery of more nutrients and oxygen, resulting in the potential for greater energy and improved cardiovascular health.

• Increase Blood Flow*
• Reclaim Your Youth*
• Increase Activity Level*
• Feel Younger*

How LRG-9 Dietary Supplement Works...

When the body produces Nitric Oxide (NO), blood flow to muscles and vital organs increases.

This allows for the delivery of more nutrients and oxygen, and potentially resulting in greater energy.

The LRG-9 formula includes 5,000mg of L-arginine and 1,000mg of L-citrulline, two ingredients that, when combined, have been shown to create natural Nitric Oxide production in the body.

Are You Deficient in Nitric Oxide (NO)?

The body’s ability to naturally create Nitric Oxide (NO), decreases with age.

You can see a sharp decrease at around 30 years of age.

The Benefits of LRG-9

HEART The LRG-9 cardio health formula has 5,000 mg of L-arginine, 1,000 mg of L-citrulline, but is also enhanced with COQ10, a powerful antioxidant to promote heart health.

BLOOD PRESSURE Nitric Oxide expands the arteries which, in turn, can help regulate blood pressure and enhances the blood flow. This enhanced blood flow can also promote healthy sexual function as well.

ENERGY One important indirect impact of Nitric Oxide on energy is that increased blood flow enables you to better maintain your core temperature balance. Your body uses less energy trying to stay

in balance, and aids in reducing general fatigue.

IMMUNE FUNCTION Nitric Oxide has been shown to aid immune function by helping fight off bacteria

and defends against infections by relaxing narrowed blood vessels, increasing oxygen and blood flow to vital organs

MUSCLE RECOVERY Nitric Oxide dilates blood vessels in the body, allowing increased blood flow to tissues. Dilating blood vessels encourages muscles in the body to relax, allowing more oxygen delivery to get to the working muscles, helping in the recovery process.

MEMORY Studies have shown increasing oxygen to the brain impacts performance by increasing the efficiency of information transfer between nerve cells in the brain.

WEIGHT LOSS has also been shown to help build muscle and reduce adipose (fat) tissue storage, which will help you lose weight and change your body. A unique product with far-reaching health benefits giving you the support necessary for a longer, healthier life.

*IMPORTANT*
REMEMBER--- LRG-9 needs to be taken on an empty stomach to be most effective.

20 Reasons to take ARGININE (LRG-9)

The Nitric Oxide derived from arginine is directly or indirectly implicated in practically every cellular response and health condition imaginable, from the cardiovascular system to the immune system, and hormone function to nerve function. Although an exhaustive list of possible applications for the amino acid is not included, the following are the primary scientifically backed reasons that anyone – even healthy people, should consider adding the arginine to their health and wellness regimen.

1. Arginine is one thousand times more powerful than any naturally occurring antioxidant in the body. Arginine`s antioxidant properties support various body systems and may protect against heart disease, stroke, cancer, and diabetes, as well as slowing premature aging. 1, 2
2. Arginine offers wide-ranging cardiovascular support, including controlling blood pressure 3, 4 and plaque formation. Nitric oxide keeps arteries relaxed and pliable for normal blood pressure, preventing hypertension and angina. 5
3. ARGININE enhances memory, 6 particularly long-term memory, and may help to reverse the effects of dementia and Alzheimer’s disease. 7
4. ARGININE boosts human growth hormone (HGH) production, which has anti-aging properties. 8
5. ARGININE enhances communication of messenger cells between nerves and the brain. 9
6. ARGININE may help improve immune function 10 and fight bacterial infections. 11
7. ARGININE may help in the treatment and prevention of diabetes since many disease complications, including poor circulation and blindness, are vascular in nature. Arginine is also found to regulate insulin secretion in the pancreas. 12, 13
8. ARGININE may inhibit the division and proliferation of cancer cells. 14, 15
9. ARGININE helps with cholesterol control by lowering serum and LDL cholesterol levels. 16
10. ARGININE enhances male sexual performance by treating vascular erectile dysfunction (ED). 17
11. ARGININE anticoagulant abilities reduce clotting to lower heart attack and stroke risk. 18
12. ARGININE reduces pregnancy-related hypertension, a risk factor for both the expecting mother and the unborn child. 19
13. ARGININE is useful in the treatment of asthma by opening pulmonary pathways for easier breathing and the treatment of lung disorders. 20, 21
14. ARGININE relaxes hypertonic sphincter muscles, preventing and healing hemorrhoids. 22
15. ARGININE boosts lean muscle mass and preserves bone density by encouraging HGH production, 23 which also leads to a reduction in fatty tissue. Because of these properties, it may be useful in weight management and strength training.
16. ARGININE can help offset cardiovascular and lung damage caused by tobacco use, 24 since Nitric Oxide levels in smokers are less than half of those found in nonsmokers.
17. ARGININE helps to accelerate wound healing 26 and post-surgery recovery. 27 Research has shown it is useful in treating burn wounds 28 and stimulates wound healing in the elderly. 29
18. ARGININE may be useful in enhancing athletic performance due to its ability to boost exercise tolerance, 30 its beneficial effect on the lungs, and its effect on HGH levels. Which helps with building lean muscle tissue.
19. ARGININE may be used to improve the function of the prostate. 31
20. ARGININE may prevent and possibly reverse the effects of osteoporosis by positively affecting bone mass. 32

Scientific Validation

1. Kochupurackal P, et al. Nitric Oxide: An Antioxidant and Neuroprotector. Annals of the New York Academy of Sciences. 2002; 962:389-401.
2. Kumar CA, Das UN. Lipid peroxides, antioxidants and nitric oxide in patients with pre-eclampsia and essential hypertension. Med Sci Monitor. 2000 Sep-Oct; 6(5):901-7.
3. 18. Brown, M.D., Dengel, D.R., Supiano, M.A. Nitric Oxide Biomarkers are As- sociated with the Blood Pressure-Lowering Effects of Dietary Sodium Restriction in Older Hypertensives. Circulation (Abstract I).1997; 96:I-539.
4. Rosano, G.M.C., Tanina, G., Cerquetani, E., Leonardo, F., Pelliccia, F., Bonfigli, B., and Chierchia, F.L. L-arginine Improves Endothelial Function in Newly Diagnosed Hypertensives. The Journal of the American College of Cardiology (Supplement A). 1998; 31:262a
5. Moncada, F., Palmer, R.M.J., Higgs, E.A. The Discovery of Nitric Oxide as the Endogenous Nitrovasodilator.Hypertension.1988; 12:365-72.
6. Pautler EL. The possible role and treatment of deficient microcirculation regulation in age-associated memory impairment. Med Hypotheses. 1994 Jun; 42(6):363-6.
7. Tarkowski E, et al. Intrathecal release of nitric oxide in Alzheimer’s disease and vascular dementia. Dement GeriatrCognDisord. 2000 Nov-Dec; 11(6):322-6.
8. Ghigo E, Arvat E, Gianotti L, et al. Hypothalamic growth hormone-insulin-like growth facto-1 axis across the human life span. J PediatrEndocrinol Metab.2000; 13 Suppl 6:1493-502.
9. Fried R, Merrell WC. The Arginine Solution. New York, NY. Warner Books, 1999.
10. Efron D, Barbul A. Role of arginine in immunonutrition. J Gastroentol. 2000; 35 Suppl 12:20-3.
11. Korting GE, Smith SD, Wheeler MA, Weiss RM, Foster HE. A randomized double-blind study of oral L-arginine for treatment of interstitial cystitis. J Urol. 1999 Feb; 161(2):558-65.
12. Piatti PM, Monti LD, Valsecchi G, et al. Long-term oral L-arginine admin- istration improves peripheral and hepatic insulin sensitivity in type 2 diabetes. Diabetes Care. 2001 May; 24(5):875-80.
13. 28. Mohan IK, Cas UN. Effects of L-arginine-nitric oxide system on chemical induced diabetes mellitus. Free RadicBiol Med. 1998 Nov 1; 25(7):757-65.
14. Heys SD, et al. Dietary supplementation with L-arginine: Modulation of tumor infiltrating lymphocytes in patients with colorectal cancer. Br J Surg. 1997 Feb; 84(2):238-41.
15. Brittenden J, et al. Dietary supplementation with L-arginine in patients with breast cancer (> 4cm.) receiving multi-modality treatment: report of a feasibility study. Br J Cancer. 1994 May; 69(5):918-21.
16. Khedara A, Kawai Y Kayashita J Kato N. Feeding rats the nitric oxide synthase inhibitor, L-N(omega) nitroarginine, elevates serum triglycerides and cholesterol and lowers hepatic fatty acid oxidation. J Nutr. 1996 Oct. ; 126(10) :2563-7.
17. Chen J, Wollman Y, Chernichovsky T, et al. Effect of high dose nitric oxide donor L-arginine in men with organic erectile dysfunction. BJU Int. 1999 Feb; 83(3):269-73.
18. 33. Wolf A, et al. Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans. J Am CollCardiol. 1997 Mar 1; 29(3):479.
19. Podjarny, E., et al. Pregnancy-induced hypertension in rats with adriamycin nephropathy is associated with inadequate production of nitric oxide. Hypertension. 1997; 29:986-991.
20. De Gouw HW, Verbruggen MB, Twiss IM, Sterk PJ. Effect of oral L-arginine on airway hyper-responsiveness to histamine in asthma. Thorax. 1999 Nov; 54(11):1033-5.
21. De Gouw HW, Marshall-Partridge SJ, et al. Role of nitric oxide in the airway response to exercise in healthy and asthmatic subjects. J Appl Physiol. 2001 Feb; 90(2):586-92.
22. Fried R, Merrell WC. The Arginine Solution. New York, New York. Warner Books, 1999.pp 4-5.
23. Stevens BR, Godfrey MD, Kaminski TW, Braith RW. High intensity dynamic human muscle performance enhanced by a metabolic intervention.MedSci Sports Exerc. 2000 Dec; 32(12):2102-8.
24. Heitzer, T., Just, H., and Munzell, T. Antioxidant Vitamin C Improves Endothelium Function in Chronic Smokers. Circulation.1996; 94:9.
25. Zeiher, A.M., Schachinger, V., and Minners, J. Long-Term Cigarette Smoking Impairs Endothelium-Dependent Coronary Arterial Vasodilator Function. Circulation.1995; 92:1094-1100.
26. Barbul A, et al. Arginine enhances wound healing and lymphocyte immune responses in humans. Surgery. 1990 Aug; 108(2):331-6; discussion 336-7.
27. Braga M, Gianotti L Raedelli G, et al. Perioperative immunonutrition in patients undergoing cancer surgery: results of a randomized double-blind phase 3 trial. Arch Surg. 1999 Apr; 134(4):428-33.
28. De-Souza DA, Greene LJ. Pharmacological nutrition after burn injury. J of Nutri. 1998 May; 128(5):797-803.
29. Kirk SJ, et al Arginine stimulates wound healing and immune function in elderly humans. Surgery. 1993 Aug; 114(2):155-9; discussion 160.
30. Bednarz B, Wolk R, Chamiec T, et al. Effects of oral L-arginine supplementation on exercised induced QT dispersion and exercise tolerance in stable anginapectoris. Int J Cardiol. 2000 Sep 15 ; 75(2-3) : 205-10.
31. Aikawa K, Yokota T, et al. Endogenous nitric oxide-mediated relaxation and nitrinergic innervation in the rabbit prostate: the change with aging. Prostate. 2001 Jun 15; 48(1):40-6.
32. Fini M, et al. Effect of l-lysine and L-arginine on primary osteoblast cultures from normal and osteopenic rats. Biomed Pharmacother. 2001 May; 55(4):213-21.
33. Sahin AS, Atalik KE, Gunel E, Dogan N. Nonadrenergic, noncholinergic responses of the human colon smooth muscle and the role of K+channels in these responses. Methods Find ExpClinPharmacol. 2001 Jan-Feb; 23(1):13-7.